McKittrick-Wheelock syndrome - Prolapsed giant villous adenoma of the rectum.
نویسندگان
چکیده
Degenerate hypersecretory villous adenoma of the rectum is an uncommon, life-threatening condition. Its diagnosis is clinically challenging since cardinal symptoms are neurological and metabolic in nature because of significant fluid and electrolyte disorders induced by severe diarrhea. Even though the condition was first described back in 1954 its pathophysiology remains unknown. Management is surgical and includes lesion excision once renal function and fluid-electrolyte parameters are brought back to normal.
منابع مشابه
Poorly Differentiated Neuroendocrine Tumor of the Rectum Coexistent with Giant Rectal Villous Adenoma Presenting as McKittrick-Wheelock Syndrome
McKittrick-Wheelock Syndrome is a rare disorder, noted for electrolyte and fluid depletion caused by secretory colorectal adenomas and carcinomas. We report here the first reported case of a 55-year-old man with a large rectal villous adenoma coexistent with a poorly differentiated neuroendocrine tumor of rectum presenting with McKittrick-Wheelock Syndrome. Palliative chemotherapy resulted in c...
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McKittrick-Wheelock syndrome is a rare disease characterized by a large hypersecretory rectosigmoid villous adenoma resulting in persistent large volume diarrhea, electrolyte abnormalities, and renal dysfunction. We report an unusual presentation of this syndrome in a patient who developed persistent diarrhea along with dermatomyositis and rectal prolapse and was later discovered to have a larg...
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McKittrick-Wheelock syndrome is a rare but recognised complication of hypersecretory rectosigmoid villous adenoma. Fluid and electrolyte imbalances require close monitoring because of large-volume losses of water, sodium and potassium. We report an unusual presentation of the syndrome associated with the development of acute pseudo-obstruction of the colon, presumably due to electrolyte dysfunc...
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Background: McKittrick-Wheelock syndrome mostly results from colorectal villous adenoma and is characterized by dehydration, hyponatremia, hypokalemia, and prerenal azotemia. Case Report: We report the case of an 84-year-old patient with rectal villous adenoma, presenting with chronic mucous diarrhea for 2 years and subsequent prerenal azotemia. After fluid and electrolyte replenishment, the pa...
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Giant tubular-villous adenoma of the rectum can determine secretory diarrhea, associated with a depleting syndrome of prerenal acute renal failure, hyponatremia, hypokalemia and hypoproteinemia. These symptoms are known as the McKittrick-Wheelock syndrome, and there are about 50 cases reported in literature. We present the case of a 59-year-old woman presented to our emergency department with a...
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عنوان ژورنال:
- Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva
دوره 105 5 شماره
صفحات -
تاریخ انتشار 2013